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Nakamura M, Ohsawa S, Igaki T (2014) Mitochondrial defects trigger proliferation of neighbouring cells via a senescence-associated secretory phenotype in Drosophila

Those with absorption issues from conditions like Crohn's or celiac disease get life-changing results because IV therapy bypasses the gut

for example, in the transparent carp model, bilirubin activated mouse AhR but failed to activate zebrafish AhR1a, suggesting potential species specificity in protective signaling mediated by endogenous ligands (Volz et al., 2008)