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The age-standardized mortality rate for smoking-related prostate cancer globally decreased from 0.279 (95% UI: 0.1300.454) in 1990 to 0.155 (95% UI: 0.0700.258) in 2021, with an average annual decline of 2.19% (95% UI: -2.29 -2.09)

Tobacco continues to be the biggest preventable cause of death worldwide with most of these deaths taking place in the Global South

But tobacco critics complained that Next actually had higher tar levels than many cigarettes, and that heavy smokers would simply smoke more Next cigarettes to give their bodies the nicotine they crave

A: Smoking is associated with premature aging and a loss of skin elasticity

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