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The first mutant Phe260Gly accepted all substrates used in the substrate scope experiment, exhibiting the lowest activity with phenol (Fig

However, most if not all of the aforementioned agents are closely associated with adverse effects including prickling sensation, contact dermatitis, irritation, high toxicity and sensitivity (7-10)

Within these comparatively autonomous mechanisms governing cell death, the introduction of Fer-1 substantially elevated cell survival rates, indicative of the effective suppression of OGD induced ferroptosis

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As a ghrelin receptor agonist, it also increases hunger