melanotic macuole Oral macula on the upper gingival mucosa on a 40-year-old Labial melanotic macule image

4.1.2 Centrilobular necroinflammation, central perivenulitis, and massive hepatic necrosis are characteristics of severe acute presentation of autoimmune hepatitis, including autoimmune-induced acute liver failure (LOE 3)

Nevi are clinically and histologically identical to the precursor lesions for melanoma in the B-K mole syndrome

REST transcriptionally represses GCLM via directly binding to its promoter region

Nonetheless, certain exceptions are noted

Li S, Ma L, Fu W, Su R, Zhao Y, Deng Y (2022) Programmable synthetic upstream activating sequence library for fine-tuning gene expression levels in Saccharomyces cerevisiae