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PLoS One 11 , e0156925 (2016)

They actually succeeded in making lipase enzymes work three times harder, increasing fat digestion from 15 percent to 45 percent of the time

however, a major issue has been that only 0.10.2 % of the antibodies reach the CNS (Pardridge 2019), and that they act against the extracellular spreading but are unable to penetrate the cells (Gaston et al