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[0145] Embodiment 138: The immunoconjugate of embodiment 136, wherein said antibody is attached directly or through a linker to one or more of the following: said drug a lipid or liposome containing said drug

767 Some evidence suggests that EPI-743 may be more potent than Idebenone

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REVUE NEUROLOGIQUE 180:357362 Rawlins M, Wexler N, Wexler A, Tabrizi S, Douglas I, Evans S, Smeeth L (2016) The Prevalence of Huntingtons Disease Neuroepidemiology 46:144153 Reedeker N, Bouwens J, Giltay E, Le Mair S, Roos R, van der Mast R, van Duijn E (2012) Irritability in Huntingtons Disease Psychiatry Res 200:813818 Reilmann R, Anderson KE, Feigin A, Tabrizi SJ, Leavitt BR, Stout JC, Piccini P, Schubert R, Loupe P, Wickenberg A, Borowsky B, Rynkowski G, Volkinshtein R, Li T, Savola JM, Hayden M, Gordon MF (2024) Safety and efficacy of laquinimod for Huntingtons disease (LEGATO-HD): a multicentre, randomised, double-blind, placebo-controlled, phase 2 study

pylori and its virulence factors disrupt the normal level of autophagy, leading to an accumulation of damaged cellular components in the early stages and triggering autophagic cell death