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What Role Does Diet Play in Male Infertility: Diet plays a critical role in male infertility by influencing sperm count, motility, morphology, inflammation, and oxidative stress, all of which affect fertility and pregnancy outcomes

Undoubtedly, the glyoxalase system, an ubiquitous enzymatic pathway, is the main detoxifying system for MG and other reactive dicarbonyl compounds in eukaryotic cells, thereby playing a major role the cellular defense against glycation and oxidative stress (Thornalley, 1993

As an example, the in vivo experiment by Azarbarz et al

Nishiwaki H, Ito M, Ishida T, Hamaguchi T, Maeda T, Kashihara K, et al

Genetically modified folate overproducing strains of some fungi and bacteria have been constructed, e.g., Ashbya gossypii , Escherichia coli , and Bacillus subtilis , the first being the best folate producer reported to date with folate titers of 6.6 mg/L (i.e., 146-fold higher than the wild strain) 631,632,633,634