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8 Mature dendritic cells tend to induce inflammatory responses that promote cartilage degradation, while immature DCs can enhance immunoregulatory responses to protect cartilage Dendritic cells (DCs) are a cluster of antigen-presenting cells that regulate inflammatory responses by secreting cytokines and inflammatory mediators associated with chronic inflammation (101)

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Curr Opin Pharmacol.2003.3(3):323-328