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First, genetic alterations in mtDNA, including mtDNA point mutations, diabetes-related mtDNA polymorphisms, ethnicity-specific mtDNA haplogroups, and low mtDNA copy number, have been reported to be associated with defective insulin secretion, insulin resistance, or both [4-8]

Ann Neurol 94:825835

PMID 16756494

S -palmitoylation typically has a cycle of palmitoylation and de-palmitoylation regulated by PATs and thioesterases, respectively [59]

For each included study, the following information was collected: first authors name, year of publication, country of origin, type of study (in vitro, in vivo, or clinical), characteristics of the experimental model (e.g., species, sample size), specific platelet-derived product used (PRP, PRGF, PRF, or PRPL), details of preparation protocols, route and frequency of administration, and main outcome measures