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Compared with the model group (inhibition 05.09%), the results indicated that all three polysaccharides inhibited the growth of HT29 cells in the xenograft model, with Dendrobium officinale polysaccharides (250 g/ml) exhibiting the most significant inhibitory effect on CRC (67.911.69%)

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Copper-based complexes, such as CuATSM and its derivative CuATSP, demonstrate enhanced activity through iron chelation and mitochondrial protection, with CuATSP showing superior permeability and ferroptosis inhibition (Lum et al., 2021