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This distinction is now unnecessary, because evidence points to a B 12 absorption pathway independent of intrinsic factor, and studies have proved that oral replacement is equal in efficacy to intramuscular therapy.9 Regardless of the test result, successful treatment can still be achieved with oral replacement therapy

de Silva TI, Liu G, Lindsey BB, Dong D, Moore SC, Hsu NS, et al

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This assumes a 5 mg/mL concentration (2 mL bacteriostatic water)

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