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Description

doi: 10.7150/ijms.44439 355

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Discovery of 7-Methyl-5-(1-[3-(Trifluoromethyl)Phenyl]Acetyl-2,3-Dihydro-1h-Indol-5-Yl)-7h-Pyrrolo[2,3-D]Pyrimidin-4-Amine (Gsk2606414), a potent and selective first-in-Class inhibitor of protein kinase r (Pkr)-like endoplasmic reticulum kinase (Perk)

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Faridar A, Jones-Davis D, Rider E, Li J, Gobius I, Morcom L, Richards LJ, Sen S, Sherr EH

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Li, S., Zhu, S

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After converting the hub genes into human genes and performing machine learning calculations, the results showed that the Stepglm[both] + Enet[alpha = 0.3] model had the highest predictive value (Fig

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