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A study analyzing the differential expression of circRNAs in eyelid tissue samples from young and older donors identified several circRNAs linked to skin aging, including hsa-circ_0137613, hsa-circ_0077605, hsa-circ_0003803, hsa-circ_0113488, and hsa-circ_0112861 (Wang et al., 2021)

His work helped overturn dogma concerning intracellular signaling by seven transmembrane receptors and provides insight into why angiotensin II has many physiologic effects in addition to blood pressure control