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Example of Calculations Pure drain and blowdown systems are uncommon as after every blowdown, the system needs to be purged of air which can be challenging while the continuous bleed systems will bleed significantly more water than designed due to the various inefficiencies of the mixing and the distance between the of the makeup water point and the bleed point

doi: 10.1038/ijo.2012.59 291 VienbergSGGeigerJMadsenSNDalgaardLT

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It is typically administered via subcutaneous or intramuscular injection in a research setting