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Ginsenoside Rg3 prevents CUSinduced reductions of 5HT levels in the prefrontal cortex and hippocampus, suggesting that its antidepressant-like effects are closely associated with the stabilization of serotonergic signaling [41]

The phase 2 CENTAUR study and its open-label extension demonstrated the safety and efficacy of AMX0035 in PALS (7)

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More help The system toxicology approach using multi-OMICS-profiling-techniques (transcriptomics, proteomics and metabolomics) have proven to be robust tool for unraveling complex molecular machinery underlying various physiological, as well as, pathophysiological processes and have been successfully utilized in various fields including stress biology and toxicology

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