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The results of the MTT assay were consistent with the results of LDH assay as CuCl 2 and Cu(OAc) 2 were able to induce significant cytotoxicity in the HaCaT keratinocytes within 24 hours, but not for GHK and GHK-Cu

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So plants have evolved plant defense mechanisms that allow them to propagate and cause a mammal that eats them, to have some type of digestive distress that keeps that mammal from coming back and wiping out that plant species