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Both processes are considered crucial for maintaining the overall functionality of the cells

Autophagy 14(2):199206

Analysis using isolated rat-liver sinusoidal-membrane vesicles

It has been shown that CypD can form complexes with A within the mitochondria of cortical neurons in APP transgenic mice, increasing the translocation of CypD from the matrix to the inner membrane (82), an essential process in the opening of the mPTP (83)