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Drue GE, Hurley S, Minor RC

In addition to hormones, various small molecules such as cytokine inhibitors including TNF inhibitors (infliximab, etanercept, ardamuzumab) and IL-6 receptor antagonists (toximab), T cell activation modulators, and abbasiprol are now utilized clinically to treat RA (101)

Understanding their classification schemes, exposure pathways, and health implications has become crucial given their pervasive environmental distribution ( Figure 1 ) ( Figure 1 2.1 Systematic classification of environmental endocrine disruptors The complexity of EED classification reflects the diverse origins and chemical properties of these compounds

USA 98 , 67366741 (2001)