melanotic vs melenic stool There are no 50 shades of melena, only one color: Black; and it's a color that smells bad. Otherwise it's not melena or it's derivatives (melenic, melanotic, melenatonic... ) Great thread w a Melanotic refers to MELANIN not

Vitamin B12 is water-soluble, meaning your body will typically eliminate any excess through urine

Analysis of oxidative stress indexes in brain tissues Took the whole brain of each group of mice after mice dying, put it in pre-cooled saline and washed quickly, absorbed the residual liquid with filter paper, weighed it precisely, prepared 10% brain tissue homogenate, centrifuged it at 3500 rpm for 10 min, collected the supernatant, and then determined the SOD, glutathione peroxidase (GSH-PX) activities and MDA content according to the instructions of the kits, expressed in U/mg, U/mg, and nmol/mg, respectively

PEDFIC 2 (NCT03659916) will provide longer-term data on the impact of odevixibat on hepatic parameters in patients with PFIC

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Benjamin DI, Brett JO, Both P, Benjamin JS, Ishak HL, Kang J, Kim S, de Morree A, Arjona M, Nutter CW, Tan JH, Dulay H, Louie SM, Nomura DK, Rando TA (2023) Multiomics reveals glutathione metabolism as a driver of bimodality during stem cell aging