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First, SELECT was not a primary prevention trial, and the data should not be extrapolated to all individuals with overweight and obesity to prevent major adverse CV events

TCA was removed with organic solvents (three volumes of 1,1,2-trichloro-1,2,2-trifluroethane: one volume of trioctylamine) in a ratio of two volumes of organic solvent to one volume of sample

doi: 10.1186/s13073-023-01178-3 137 JiangFJiangYZhiHDongYLiHMaSet al

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Rosenberg JM, Harrell C, Ristic H, Werner RA, de Rosayro AM