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To replicate and verify whether glucose secretion induced by metformin in organoids, we measured the amount of glucose in the medium from monolayer-seeded colon organoids

Rosacea is a chronic skin condition that causes redness, visible blood vessels, and sometimes small, red, pus-filled bumps on the face

These systems allow researchers to measure endpoints such as glycerol release, fatty acid oxidation, gene expression changes, and receptor signaling activity under controlled laboratory conditions

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These metabolic benefits translate into whole-body effects: for example, in diet-induced obesity models, MOTS-c administration prevented excessive weight gain and insulin resistance when mice were fed a high-fat diet, without affecting weight in lean diets