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Cryo-EM data were collected on a Tecnai Arctica (FEI, Hillsboro, OR) at 200 kV, utilizing an energy filter and a direct electron detector (Gatan, Pleasanton, CA) operated by EPU software (Thermo Fisher Scientific, Waltham, MA)

Ranson H, Claudianos C, Ortelli F, Abgrall C, Hemingway J, Sharakhova MV

This simplified the trial design but raises legitimate questions about whether weight-based dosing might improve outcomes

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