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Interestingly, it was reported that GH is not required for normal intrauterine growth, a finding supported by evidence that GH deficiency/insensitivity does not associate with a significant reduced size at birth[3135]

Even though PCFT is often coexpressed with RFC1, PCFT function would be minimal and possibly may not contribute to the delivery of folate systemically

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To further investigate the mechanism underlying STAT3 downregulation, we examined the protein expression levels of its upstream signaling molecule, JAK2, and phosphorylated JAK2 (p-JAK2)