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To ensure that these results were not impacted by a differential influence of the different knockdowns on cell viability, we monitored the silenced cells for compromised health using the nucleic acid dye SYTOX, which cannot cross the plasma membrane of healthy cells

Regulation of human cystathionine beta-synthase by S-adenosyl-l-methionine: evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region

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and facilitating access to community-based social services to address unmet HRSN (for example, housing, utilities, transportation, food assistance) to address the SDOH need(s)