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Acromegaly is treated by reducing GH levels or GH actions to the level by which IGF-1 normalizes, and T1DM is treated by insulin until HbA1c levels normalize [1-4]

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Ferrucci et al., According to the American Federation for Aging Research ( predict remaining life expectancy better than chronological age, monitor mechanisms underlying the aging process but not a specific disease, be subject to repeated tests without harming the individual, be testable in both laboratory animals and humans

Nonetheless, further experiments, for example in ovariectomized animals supplemented with or without E2, would be required to investigate this