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Following repeated antigenic stimulation, high expression of PD-1 and other co-inhibitory molecules has been identified as an indicator of T-cell exhaustion and dysfunction, particularly in cells isolated from the tumor microenvironment (63)

doi: 10.1021/jm070037v

It can be taken intravenously, orally (swallowed by mouth), or by inhalation by use of a nebulizer

54 Conversely, the P

Am J Respir Crit Care Med 166(4):510513 Lok SS, Stewart JP, Kelly BG, Hasleton PS, Egan JJ (2001) Epstein-Barr virus and wild p53 in idiopathic pulmonary fibrosis