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2,4-D owes its popularity in application to its physical and chemical properties such as selectivity, broad-spectrum application and low cost

The logic is that sustained exposure over a longer window may matter more than peak concentration particularly for an epigenetic mechanism that operates through gene expression changes, which take time to manifest

Sample sizes were determined by data availability in each cohort

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11) are consistent with our observation that size of the aggresome-like compartment per se does not correlate with high exopher levels and aggresome-like organelle size does not predict extrusion (Supplementary Fig