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10.3390/ijms24065238 9 Al-ChalabiA.HardimanO

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189 In contrast, from a prophylactic approach, another research group proposed what they deemed a cost-effective approach of yearly injections of 1000 g of vitamin B12 to every patient on metformin to reduce the risk of deficiency and also stated that this could remove the requirement for annual screening, though this has not been empirically tested

Challenges persist, however, including stringent regulatory landscapes across different regions concerning claims and ingredient safety, potential consumer skepticism about product efficacy, and the need for brands to differentiate in a crowded marketplace