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Description

Acrolein-induced cytotoxicity in cultured human bronchial epithelial cells

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Although YBX1 may control the translation of multiple targets beyond AMPK1 and other RBPs may also affect AMPK expression, AMPK translation control through the -KGTETYBX1 cascade represents an important metabolicepigenetic crosstalk that sustains human cancer cell survival under energy stress

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In ALS, there is an abnormal cytoplasmic aggregation of misfolded proteins, mainly DNA-binding protein 43 (TDP-43), and fused in sarcoma (FUS) (Wijesekera and Leigh 2009)

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