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Pediatric pharmacokinetics and long-term safety require clarification, particularly for polyphenols and carotenoids with intrinsically low oral bioavailability and potential interactions with conventional medications like antipsychotics or stimulants (Hendouei et al., 2020

This probably goes without saying, but that can be extremely painful

Small, uncontrolled, open-label intervention studies have suggested a beneficial effect of acetyl-L-carnitine (ALCAR) in patients with painful neuropathies