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References 1 MartinezFOGordonS

Identifier NCT03467932, A Study to Evaluate the Efficacy and Safety of ORMD-0801 (Oral Insulin) in Patients With Type 2 Diabetes Mellitus , (2018)

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supported this in their study, using a novel multi-epitope vaccine to intensify the Th2 cytokines IL-10 and IL-4 in diabetic mice, amplifying the Th2-like immune response, and regulating the Th1/Th2 ratio imbalance

Apigenin proved to suppress the inflammation and allergic responses elicited by macrophages and mast cells, while also improving the skin barrier, and hence may be a treatment option for atopic dermatitis