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Description

irAEs refractory to glucocorticoids may require the administration of a mAb targeting TNF- (i.e., infliximab) to treat certain irAEs such as colitis (16, 136, 237, 245) and pneumonitis (25, 175, 246)

J.GauppC.RogerT.Shankar-HariM.et al (2022)

doi: 10.1073/pnas.1220484110 233 VerkhratskyA.Rodriguez-ArellanoJ

Safety and feasibility of this approach have been validated in 7 cohort studies 5966 on individuals affected by discogenic LBP ( stage II according to Pfirrmann grading) not responsive to standard conservative treatments