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Description

The primary theoretical concern is that sustained NAD+ elevation through chronic NNMT inhibition could activate pathways (PARP, SIRT1) that have context-dependent roles in cancer biology NAD+ supports DNA repair and cellular longevity, but also fuels rapidly dividing cells

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BPC-157 is stable in simulated gastric fluid at pH 1.2 for up to 24 hours in vitro, but actual bioavailability in live models depends on enzymatic degradation by pepsin and trypsin