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En modelos de obesidad inducida por la dieta, se ha observado que esta inhibicin reduce la acumulacin de grasa blanca y promueve la liplisis, reprogramando eficazmente las vas metablicas para un mayor gasto energtico

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Moreover, clinical studies suggested that estradiol treatment was able to revert endothelial dysfunction in post-menopausal women with atherosclerotic, non-stenotic arteries by preventing acetylcholine-induced coronary vasospasm (114)