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Acknowledgements While preparing the manuscript, the authors used ChatGPT to frame complex information into a cohesive outline while maintaining intellectual integrity

Male WT mice and male GLP-1R knockout mice, aged 713 weeks with weighing 2030 g were included in this study [29]

Accessed March 24, 2026.

Hockel, M., Schlenger, K., Hockel, S

Since this model results in extremely elevated and debilitating glucose levels, titration to non-toxic levels of hyperglycemia was achieved with daily injections of long-acting insulin glargine ( Fig