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Description

1999;277:R856R862

doi: 10.1158/0008-5472.CAN-11-2182 535 HutzenBFriedmanLSoboMLinLCenLDe AngelisSet al

The thyroid is controlled through the hypothalamus-pituitary-thyroid axis, which is prone to circadian and seasonal changes

However, it has also been suggested that CR-induced metabolic effects may be due to decreased protein intake in food-restricted animal models 4,5

Histidine, lysine, and arginine are considered basic amino acids because each of their side chains has a nitrogen containing group that can exist in either a protonated or deprotonated form