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First, LDX induces activation of the known dopaminergic and adrenergic receptors DA receptor 1A (DRD1), DA receptor 1B (DRD5), DRD2, ADRA2A, ADRA2B and alpha-2C adrenergic receptor (ADRA2C) [155, 158, 159], contributing to neurotransmission signalling
The N-terminus of TDP-43 promotes its oligomerization and enhances DNA binding affinity
Perspektivy farmakoterapie vychzejc z etiologickch poznatk Pokud bychom mli vybrat jednu spolenou charakteristiku, kter je typick pro etiologii jak DPN, tak i CIPN, byl by to oxidan stres a VKR, kter se podlej na pokozen neuron
Lim JU, Lee J-H, Kim T-H, Lee JS, Lee S-D, Oh Y-M, Rhee CK
Samples were covered in a 10-nm gold layer using a (JEOL JFC-1100E) gold sputter device
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