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Lack of sleep can reduce circulation, making the skin appear dull and emphasizing the blood vessels underneath

Deficiency in B12 can lead to demyelination, resulting in neurological symptoms such as numbness, tingling, impaired coordination, and cognitive decline

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This attenuation is reduced in Tbx1 +/ mice across a range of prepulse intensities (2)

For example, studies by Lindenbaum et al 38 and Healton et al 5 showed that up to 28% of patients with neuropsychiatric symptoms of B 12 deficiency can present with normal mean corpuscular volume (MCV), hematocrit (HCT), or both