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In animal-based foods, vitamin B12 binds to the protein molecules

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Best time of day Injectable: Morning administration aligns with natural cortisol rhythms and allows any mild side effects to resolve before sleep

So, if you are eating a varied diet and do not have a laboratory-documented vitamin B12 deficiency, you do not need additional supplementation. However, she explains people who subscribe to strict vegan or vegetarian diets are much more likely to be at risk of vitamin B12 deficiency, and they should take supplemental B12, especially when pregnant or trying to become pregnant