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The research involved 72 patients with T2DM, out of which 41 received metformin at a dose of 1700 mg per day for at least 12 months, while 40 age- and sex-matched individuals served as control subjects

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Dosing Considerations While this article is educational and not prescriptive, its worth noting that reported dosages in the biohacking and wellness communities typically range from 250mcg to 1000mcg daily, often split into one or two doses

Diagnoses of psychiatric or affective disorders were determined by asking the following questions: Do you have a psychiatric or affective diagnosis? Have you taken a pharmacological treatment or received psychological therapy? Additionally, some medical conditions exceed the normal range of hematological parameter counts and antioxidant levels

doi:10.1038/nrm2871