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Patient characteristics are shown in Table 1

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When standard, unformulated glutathione is ingested, the highly acidic environment of the stomach (which has a pH of less than 1.5) and the aggressive digestive enzymes (peptidases) in the small intestine rapidly cleave the tripeptide into its three constituent amino acids

Third, the one-week washout interval, although sufficient to reverse most clinical effects, may not completely eliminate slower-resolving mediators, potentially attenuating periodtoperiod contrasts