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In studies that show alteration, T4 and reverse T3 (rT3) have been found to be increased along with normal T3 levels in some studies,[] whereas others report an increase of T3 only without accompanying rise of T4.[] One study reported higher levels of free T3 (fT3) and free T4 (fT4) in smokers.[] A decrease in the levels of both T4 and T3 has also been reported by some.[] Accompanying TSH levels were found to be low in most[] and normal in some studies.[] Interpreting all these results, smoking seems to have either no effect on thyroid function or a weak thyroid-stimulating effect in normal adults, causing small, thyrotrophin independent increases in T4, and more commonly in T3 levels.[] Indeed in a Norwegian population survey of 20,479 women and 10,355 men without previously known thyroid disease, the authors reported the prevalence of overt hypothyroidism to be lower in current smokers compared with never smokers (odds ratio, 0.60), whereas the prevalence of overt hyperthyroidism was higher among current smokers (odds ratio, 2.37) than never smokers.[] A Korean study similarly reports smoking to be associated with a lower prevalence of subclinical hypothyroidism in noniodine deficient normal population.[] In contrast to the thyroid-stimulating effect in healthy subjects, tobacco smoke has been implicated to have an antithyroid effect in Iodine deficient areas
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Lansbury then received an education at South Hampstead High School from 1934 until 1939, [11] where she was a contemporary of Glynis Johns
