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As semaglutide can cause nutritional deficiencies such as vitamin B12 deficiency, many clinicians believe that maintaining optimal B12 levels can reduce fatigue, improve tolerance, and promote overall health during semaglutide therapy

With this study, we aim to provide new therapeutic insights for optimizing postoperative gastrointestinal function recovery, particularly in utilizing simple and low-cost treatments such as vitamin B1 and B12, thereby promoting their clinical application

Substantial pharmaceutical research base, including FDA approval for HIV-associated lipodystrophy (under the brand name Egrifta in pharmaceutical formulation)

(2019) Effect of two different sublingual dosages of vitamin B(12) on cobalamin nutritional status in vegans and vegetarians with a marginal deficiency: A randomized controlled trial

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