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But it can also come on gradually from a slow-growing brain tumor or a disease that causes progressive, permanent damage (degenerative)." FTD consists of incurable disorders that cause degeneration in the frontal and temporal lobes of the brain, leading to "an inevitable decline in functioning" for the patient, according to the Association for Frontotemporal Degeneration (AFTD)

Phase I study of taminadenant (PBF509/NIR178), an adenosine 2A receptor antagonist, with or without spartalizumab (PDR001), in patients with advanced non-small cell lung cancer

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Interestingly, the transcriptional expression of AtARR6 in OE lines was decreased under control conditions but was increased under cold stress compared with WT (Figure 8)

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