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( A and B ) C57BL/6 mice were injected i.p

ROS, cell senescence, and novel molecular mechanisms in aging and age-related diseases

After FOXO4-DRI treatment, the staining of FOXO4 and p53-pS15 became weaker in the nucleus at 48 h and then disappeared with an accumulation in the cytoplasm at 72 h, especially in keloid fibroblasts