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Phospholipid peroxidation as a factor in gallstone pathogenesis

Activated caspase-3 further promotes Ca 2+ release, creating a vicious cycle that amplifies caspase-3 activation and ultimately results in oocyte apoptosis

432,433 Current guidelines recommend that endoscopic interventions should be considered for patients who have failed conservative management and who have aseptic WON with compression of adjacent organs (e.g., the biliary tract or gastrointestinal tract) or who persist in pain 4 weeks after the onset of AP

[0330] Alternative transchromosomic animal systems expressing human immunoglobulin genes are available in the art and can be used to raise anti-ALPP/ALPPL2 antibodies contemplated herein

In patients receiving long-term administration of glycyrrhizin or GA, serum levels of 3MGA are significantly elevated (Kato et al., 1995)