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Induction of HO-1 results in the release of CO, which regulates the activity of transcription factors such as NRF-1 and PGC-1 through the Akt, AMPK, MAPK, and Sirt1 pathways, thereby promoting the expression of these transcription factors and the generation of antioxidant enzymes involved in mitochondrial biosynthesis

The evolution of the GPCR signaling system in eukaryotes: modularity, conservation, and the transition to metazoan multicellularity

The effect of various interventions on the prevention of radiation dermatitis: a network meta-analysis

It also helps recycle other antioxidants, such as Vitamin C and Vitamin E, making your entire antioxidant defense system more efficient

Selenium supplementation and oxidative stress: a review