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Virology 610, 110616

doi: 10.1016/j.neuroimage.2018.05.070

Ozone therapy versus hyaluronic acid injections for pain relief in patients with knee osteoarthritis: preliminary findings on molecular and clinical outcomes from a randomized controlled trial

PMID: 1993213

We demonstrate that mechanical stress induces ROS accumulation and inflammatory cytokine expression in cultured chondrocytes in vitro and that both are inhibited by treatment with the anti-oxidant N-acetyl cysteine (NAC)