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[DOI] [PubMed] [Google Scholar] 501.Menon S., Shrudhi Devi K.S., Agarwal H., Shanmugam V.K

Redox imbalance and genetic mutations in heart failure: synergistic mechanisms and therapeutic strategies

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ROS signaling regulates transcription factors, such as AP-1 and nuclear factor-kappa B (NF-B), inducing the expression of matrix metalloproteinases (MMPs) that can induce collagen oxidation and reduce the expression of types I and III collagen [26]