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cruzi manipulates the hosts immune response

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18 , 19 Remarkably, tumours with a high-mesenchymal/EMT-like phenotype, including sarcomas (of mesenchymal origin), claudin-low/mesenchymal-like triple-negative breast cancers (TNBC), mesenchymal subtype glioblastoma, and CMS4 (mesenchymal) colorectal cancers, are among the most drug-resistant malignancies